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Prof. Tolosa

Eduardo Tolosa, MD, FRCP

MD degree from the University of Barcelona, Spain. He obtained his neurological training at the University of Minnesota Hospital in Minneapolis. He was Visiting Scientist at Brookhaven National Hospital were ha worked with George Cotzias during 1974 and 1975, and subsequently he joined the faculty of the Department of Neurology at the University of Minnesota. He was later appointed Chief of Neurology at the University Hospital in Barcelona in 1982. He is Professor of Neurology at the University of Barcelona and the Director of the Parkinson Disease and Movement Disorder Centre at the University of Barcelona Hospital.

Prof. Tolosa was certified as a neurologist by the American Board of Neurology and Psychiatry in 1976. He became a Fellow of the in 1997. He is a Fellow of the American Academy of Neurology and the American Neurological Association and of the Royal College of Physicians and founding member of the Movement Disorder Society (MDS) . He has been President of this Society and President of the European Neurological Society. Prof. Tolosa is an honorary member of several neurological societies including the British Neurological Association and the French Neurological Society.

Prof. Tolosa's research and publication activities have brought him appointments to various peer-review journals. He is, for example, a member of the International Advisory Committee of the Archives of Neurology and has served as member of the editorial board of the European Journal of Neurology, Movement Disorders, Practical Neurology, the Journal of Neurology Neurosurgery and Psychiatry and the Journal of Neurology.

Prof. Tolosa research interest have centered on movement disorders and particularly in issues related to experimental therapeutics, etiology and pathophysiology of various Parkinson syndromes. His team has investigated on the clinical and molecular genetics of Parkinson disease and progressive supranuclear palsy. They demonstrated that an extended tau gene haplotype (H1E) in its homozygous state is overrepresented in PSP and described the only homozygous tau mutation so far in patients with PSP syndrome. He has also investigated in collaboration with neurophysiologist in his department brainstem mechanisms underlying several movement disorders such as dystonia and the various Parkinson syndromes defining the presence of brainstem abnormalities in various focal dystonias and atypical parkinsonisms.

In the areas of experimental therapeutics Prof essor Tolosa was involved in pioneer studies defining mechanisms underlying levodopa related motor fluctuations, both, in patients and in animal models of parkinsonism and his team has been among the first in Europe to evaluate efficacy of novel surgical strategies for Parkinson disease such as subthalamic nucleus stimulation and its impact upon patients cognition and quality of life.